When you ask for a best-of list from John Waters, you know he's going to be brutally honest, and definitely unique. No blockbusters here...except Brüno ("Sometimes audiences get what they deserve.").
His top choice was Import Export, of which he says, "The miserable lives of Ukrainian immigrants in Vienna make this agonizing but brilliantly directed opus the cinematic equivalent of slitting your wrists. A new genre? Depression porn? Hey, I got off."
Second choice? Antichrist. Well, yeah.
I will, however, greatly disagree on his inclusion of Bobcat Goldthwait's World’s Greatest Dad. It deserved to be a bomb.
Check out the full list at ArtForum.